Saint Clément (au-dessus : La Vierge de l'Annonciation)

Saint Clement with the Virgin of the Annunciation from 1457 combines a papal saint with the Annunciation theme in a multi-register composition typical of Italian altarpiece design. The inclusion of Pope Clement suggests a specific institutional or patron connection to the papal tradition Altarpieces featuring rows of standing saints served both liturgical and devotional functions, identifying the church's patron saints and giving worshippers specific objects for personal prayer.

The stacked composition separates the saint below from the Annunciation above, with Giovanni di Paolo's rich color and gold tooling creating visual unity across the registers.