Saint Sebastian tended by Saint Irene

Saint Sebastian Tended by Saint Irene from around 1630 depicts the young martyr being nursed after his first martyrdom. Gentileschi's treatment of the scene emphasizes the tender care of the female saint rather than the male saint's suffering. Artemisia Gentileschi's powerfully direct treatment of female subjects—heroines, saints, and biblical figures depicted with unprecedented psychological force and physical credibility—makes her one of the most significant figures in the Baroque tradition.

The composition focuses on Irene's ministering to Sebastian with Caravaggist lighting. Gentileschi's naturalistic handling of both figures creates a scene of compassionate care.